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Meta Analysis Overview:

A critical user guide and complete dossier to usage modalities, concepts, and associated faculties. This informational assay is a broad scope meta-analysis of publicly available research and studies up to calendar year 2022; as well as internal quantitative analysis done up to present day. Information contained within should not be taken nor substituted for that of your general practitioner or family physician. Depending upon local regulation, users may need a prescription or referral from a healthcare provider to undergo Hyperbaric Oxygen Therapy (HBOT). HBOT is considered a medical treatment and is predominantly administered in clinical settings under the supervision of trained healthcare professionals.

Safety Information, Release & Liability:

Your healthcare provider is best qualified to assess your medical condition; review your medical history and determine how HBOT is best suited for your specific needs. You may be issued a prescription or referral for HBOT if required by local regulation. It's important to follow the guidance of your healthcare provider and receive HBOT treatments under the appropriate guidance to ensure proper safety and maximum efficacy. Additionally, insurance coverage for HBOT may require a prescription or referral from a healthcare provider for user reimbursement. Exercise with Oxygen Therapy (EWOT) typically does not require a prescription as it is considered a form of physical exercise rather than a medical treatment. However, it's important to note that individuals with certain medical conditions or health concerns should consult with a healthcare provider before starting any new exercise program, including EWOT. While a prescription may not be necessary for EWOT, it's advisable to seek guidance from a qualified healthcare professional, such as a physician, physical therapist, or exercise physiologist, especially if you have underlying health issues or concerns. They can provide personalized recommendations, assess your fitness level, and ensure EWOT is safe and appropriate for your individual needs. For all equipment and devices, it is essential to follow the manufacturer's instructions and safety guidelines to minimize risk of injury, as well as to ensure maximized user benefits.

Notes from the Author on Item Selection and Purpose:

Welcome to your crash course, overview, and user guide to all things Hyperbaric and Exercising with oxygen. In effort to not make this compendium too long, we’ll be focusing on a basic understanding of how these devices work, short but detailed examples of benefits and proclivities, and a larger working database of brief concepts for application, both for private users and commercial offices. In this syllabus you may notice overlapping trends for usage, and recurring compositional influence across use and benefits of both HBOT and EWOT. Both amazing resources begin their anthropology of utility and physiological adaptation in the same place: OXYGEN. In the first dichotomy for understanding usage, one immediate difference is clear; one is used ACTIVELY, and one is used in LATENTLY. While it may seem obvious and simple, this fundamental difference foreshadows influence across virtually all use cases and informs the genius behind each machine and practical application. In a short, the ACTIVE apparatus (EWOT) to some degree tends toward performance enhancement; the LATENT apparatus (HBOT) toward physiological resilience. This is not to say however, that either machine fails to do one or the other. In fact both devices support performance and resilience. Let’s take a closer look at one example of that concept to set the table for their greater applications. We will begin by looking at a handful of the Benefits to the Cardiovascular System to illustrate how both machines, neighbors in a larger toolbox of optimization and wellness tools, utilize adjacent concepts of oxygen use. Before reading on, take a moment to consider how these different machines may influence cardiovascular health; bear in mind one is used with active exertion in the presence of pure oxygen, while the other is a static use under pressure, in the presence of pure oxygen.

Note on Mode of Action for EWOT:

While the understood action of increasing O2 saturation in HBOT usage is clearly identified in the changing of partial pressure of oxygen due to pressure, the mechanism for increased saturation due to EWOT is slightly more nuanced. While a simple blood assay can confirm the increase in O2 saturation from EWOT, the context behind the change is more nuanced. Breathing high levels of O2 increases oxygen delivery to muscles, and in turn leads to a temporary increase in blood pressure, this has a microcosm effect of O2 pressure increase within blood vessels and arterial pathways. The supplementation of pure or near pure oxygen during EWOT also increases the amount of oxygen that can bind to hemoglobin, allowing for a temporary overall increase in blood profile and musculoskeletal oxygenation. Due to the increased O2 levels in the lungs and alveoli, this gradient shift of saturation dictates a greater respiratory diffusion of oxygen into the bloodstream, to the hemoglobin molecule, and then offloaded during blood circulation to lower saturation cells during travel, where it is utilized for cellular respiration across all modes of cellular function in the body.


Vasodilation and Blood Vessel Health:

After getting on the bike with pure oxygen coming into your mask, brief and methodically periodized physical exercise will begin to invite the oxygen into every cell in the body, faster and with greater saturation than you may have ever experienced before. This in turn allows for healthy and robust vasodilation or widening of blood vessel diameter. There is an increase in heart stroke volume, blood vessel size, and blood pressure; all contributing to healthy, flexible blood vessels. Elasticity is also enhanced by the alkalizing presence of pure oxygen, reducing the brittleness of thin cell walls exacerbated by the high acidity of high levels of CO2.

During exercise with supplemental oxygen, even more oxygen is delivered to tissues, including to blood vessel walls. Just a few hundred nanometers wide, healthy endothelial walls effectively regulate blood pressure, and improve physical performance. The flexible and oxygenated conduit maintains healthy intracellular metabolism, tissue repair, and vascular integrity. EWOT makes sure they are enriched with enough oxygen to do their job at any level of physical output across the body. This high tensile strength and yet flexible network gets a chance to recuperatively indulge and reset in the presence of pure O2.

By expanding the blood vessels during an oxygenated workout, we’re also offering a critical ingredient for upregulating muscle synthesis, fat loss, cognitive health, and more. This alkalized vasodilation leads to healthy markers in all endothelial function. On the other hand, with HBOT use, we have vasoconstriction, but how would that compare in terms of benefit or use?